Tomaymycin DM
Tomaymycin DM is a tomaymycin derivative, PBD monomer, and DNA alkylating agent. Tomaymycin DM can serve as a payload in tumor-targeting antibody-conjugated active molecules (ADCs) .
Product Specifications
CAS Number
945490-09-5
UNSPSC
12352203
Target
ADC Payload
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Tomaymycin_DM.html
Purity
95.73
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1N2[C@](CC(C2)=C)([H])C=NC3=CC(O)=C(OC)C=C13
Molecular Formula
C14H14N2O3
Molecular Weight
258.27
References & Citations
[1]Dr. Julia Mantaj, et al. From Anthramycin to Pyrrolobenzodiazepine (PBD) -Containing Antibody–Drug Conjugates (ADCs) . Angew Chem Int Ed Engl. 2017 Jan 9; 56 (2) : 462–488.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Pyrrolobenzodiazepines
Available Sizes
Frequently Asked Questions
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