Tomaymycin DM
Tomaymycin DM is a tomaymycin derivative, PBD monomer, and DNA alkylating agent. Tomaymycin DM can serve as a payload in tumor-targeting antibody-conjugated active molecules (ADCs) .
Product Specifications
CAS Number
[945490-09-5]
UNSPSC
12352203
Target
ADC Payload
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Tomaymycin_DM.html
Purity
95.73
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1N2[C@](CC(C2)=C)([H])C=NC3=CC(O)=C(OC)C=C13
Molecular Formula
C14H14N2O3
Molecular Weight
258.27
References & Citations
[1]Dr. Julia Mantaj, et al. From Anthramycin to Pyrrolobenzodiazepine (PBD) -Containing Antibody–Drug Conjugates (ADCs) . Angew Chem Int Ed Engl. 2017 Jan 9; 56 (2) : 462–488.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Pyrrolobenzodiazepines
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1229987-01 0.02 mg (E-Coli)
Recombinant Schizosaccharomyces pombe Chromatin-associated protein swi6 (swi6)
Ask
View Details MBS1229987-02 0.02 mg (Yeast)
Recombinant Schizosaccharomyces pombe Chromatin-associated protein swi6 (swi6)
Ask
View Details