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Mn-Superoxide Dismutase, Recombinant

Superoxide dismutase (SOD) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a critical role in the defense of cells against the toxic effects of oxygen radicals. SOD competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice by preventing the conversion of NO to peroxynitrate, an inducer of apoptosis.

Product Specifications

CAS Number

9054-89-1

Applications

SOD is a unique enzyme which caneliminate superoxide radical, thus protecting the cell from superoxide toxicity. SOD is widely used for adjusting endocrine system and immunity enhancement, in clinical and research of inflammation, such as therapy rheumatoid arthritis, Multiple chronic arthritis, myocardial infarction, angiocardiopathy, cancer patients.

Activity

~15,528 U/mg protein

Storage Conditions

4°C, store at -20°C for long-term preservation.

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