Native Baker's yeast (S. cerevisiae) Carboxypeptidase Y

Carboxypeptidase Y (CPY) catalyzes the following reaction: Peptidyl-L-amino acid + H2O ------> Peptide + L-amino acid. It is prepared according to the method of Moore & Stein (J. Biol Chem, 211, 907, 1954) . It resembles Carboxypeptidase A in its substrate specificity, but it hydrolyzes C-terminal glycine and L-leuicine more rapidly and L-phenylalanine more slowly.