BRD4 Inhibitor-24
BRD4 Inhibitor-24 (compound 3U) is a potent BRD4 inhibitor, BRD4 Inhibitor-24 shows antitumor activity against MCF7 and K652 cells, with IC50 values of 33.7 and 45.9 μM, respectively (extracted from patent CN107721975A) [1].
Product Specifications
CAS Number
[309951-18-6]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brd4-inhibitor-24.html
Purity
99.27
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C1=CC=C(C(OC)=C1)OC)NC2=NOC(C)=C2
Molecular Formula
C13H14N2O4
Molecular Weight
262.26
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Yao Zhiyi, et al. BRD4 micromolecular inhibitors, synthetic method and its application with antitumor activity. CN107721975A
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BRD4
Available Sizes
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