BTK-IN-37
BTK-IN-37 (compound 8d) is a BTK inhibitor that can induce apoptosis in cancer cells. BTK-IN-37 targets BTK with Ki and IC50 of 5.07 nM and 3.6 nM, respectively. BTK-IN-37 can also selectively induce enrichment of genes involved in necroptosis and pyroptosis[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Btk
Type
Reference compound
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/btk-in-37.html
Smiles
O=C(C1=CN=C(S(=O)(C)=O)N=C1N2CC(N3N=C(C4=CC=C(OC5=CC=CC=C5)C=C4)C6=C(N)N=CN=C63)CCC2)NC
Molecular Formula
C29H29N9O4S
Molecular Weight
599.66
References & Citations
[1]Exploring 2-Sulfonylpyrimidine Warheads as Acrylamide Surrogates for Targeted Covalent Inhibition: A BTK Story
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PH318358 10 µg
Monoacylglycerol Lipase (MGLL) (NM_007283) Human Mass Spec Standard
Sign In for Pricing
View Details VAng-Yyj0094-50gEcoli 50 µg (E. coli)
Recombinant Mycobacterium Tuberculosis mbtL Protein (aa 1-84)
Sign In for Pricing
View Details