Ingenol
Ingenol is a PKC activator, with a Ki of 30 μM, with antitumor activity.
Product Specifications
CAS Number
[30220-46-3]
Product Name Alternative
(-) -Ingenol
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PKC
Type
Natural Products
Related Pathways
Epigenetics; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Ingenol.html
Purity
99.51
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@]([C@@H](C(CO)=C[C@@]1([H])[C@H](C2(C)C)[C@H]2C3)O)([C@H]4O)[C@]([C@@H]3C)(C=C4C)C1=O
Molecular Formula
C20H28O5
Molecular Weight
348.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Hasler CM, et al. Specific binding to protein kinase C by ingenol and its induction of biological responses. Cancer Res. 1992 Jan 1;52 (1) :202-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
PKC
Available Sizes
Curated Selection
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