Nrf2 activator-11
Nrf2 activator-11 (compound M11) is a Nrf2 activator with blood-brain permeability. Nrf2 activator-11 has anti-oxidation, anti-inflammation, anti-ferroptosis and anti-apoptosis. Nrf2 activator-11 can be used to study cerebral ischemia-reperfusion (CI/R) injury models[1].
Product Specifications
CAS Number
[3069351-39-6]
UNSPSC
12352005
Target
Apoptosis; Keap1-Nrf2
Type
Reference compound
Related Pathways
Apoptosis; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nrf2-activator-11.html
Smiles
O=C(C1=C(O)C=C(C)C=C1)NCCC2=CNC3=CC=C(N(C)C)C=C32
Molecular Formula
C20H23N3O2
Molecular Weight
337.42
References & Citations
[1]Wu G, et al. Design, synthesis and biological evaluation of N-salicyloyl tryptamine derivatives as multifunctional neuroprotectants for the treatment of ischemic stroke. Eur J Med Chem. 2024 Nov 15;278:116795.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
041370 200 µL
S39A8, ID (SLC39A8, BIGM103, ZIP8, Zinc transporter ZIP8, BCG-induced integral membrane protein in monocyte clone 103 protein, LIV-1 subfamily of ZIP zinc transporter 6, Solute carrier family 39 member 8, Zrt- and Irt-like protein 8)
Ask
View Details 