Nrf2 activator-11
Nrf2 activator-11 (compound M11) is a Nrf2 activator with blood-brain permeability. Nrf2 activator-11 has anti-oxidation, anti-inflammation, anti-ferroptosis and anti-apoptosis. Nrf2 activator-11 can be used to study cerebral ischemia-reperfusion (CI/R) injury models[1].
Product Specifications
CAS Number
3069351-39-6
UNSPSC
12352005
Target
Apoptosis; Keap1-Nrf2
Type
Reference compound
Related Pathways
Apoptosis; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nrf2-activator-11.html
Smiles
O=C(C1=C(O)C=C(C)C=C1)NCCC2=CNC3=CC=C(N(C)C)C=C32
Molecular Formula
C20H23N3O2
Molecular Weight
337.42
References & Citations
[1]Wu G, et al. Design, synthesis and biological evaluation of N-salicyloyl tryptamine derivatives as multifunctional neuroprotectants for the treatment of ischemic stroke. Eur J Med Chem. 2024 Nov 15;278:116795.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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