Ferutinin
Ferutinin, a natural terpenoid compound, is an estrogen receptor ERα agonist and estrogen ERβ-receptor agonist/antagonist with IC50s of 33.1 nM and 180.5 nM, respectively. Ferutinin acts as an electrogenic Ca2+-ionophore that increases calcium permeability of lipid bilayer membranes, mitochondria. Ferutinin possesses estrogenic, antitumor, antibacterial and antiinflammatory activities[1][2].
Product Specifications
CAS Number
41743-44-6
UNSPSC
12352005
Target
Apoptosis; Estrogen Receptor/ERR
Type
Natural Products
Related Pathways
Apoptosis; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Infection; Endocrinology; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ferutinin.html
Purity
99.23
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(O[C@@H]1[C@@]2([H])[C@@](C(C)C)(O)CC[C@]2(C)CC=C(C)C1)C3=CC=C(O)C=C3
Molecular Formula
C22H30O4
Molecular Weight
358.47
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
ERα; ERβ
Available Sizes
Frequently Asked Questions
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