JNJ 2408068
JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ 2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg[1].
Product Specifications
CAS Number
[317846-22-3]
Product Name Alternative
R170591
UNSPSC
12352005
Target
RSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/jnj-2408068.html
Purity
96.57
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C)N=C1CN2C3=CC=CC(C)=C3N=C2NC4CCN(CCN)CC4
Molecular Formula
C22H30N6O
Molecular Weight
394.51
References & Citations
[1]Wyde PR, et al. Short duration aerosols of JNJ 2408068 (R170591) administered prophylactically or therapeutically protect cotton rats from experimental respiratory syncytial virus infection. Antiviral Res. 2003 Nov;60 (3) :221-31.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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