Phentolamine (hydrochloride)
Phentolamine hydrochloride is an orally active adrenergic α receptor-blocking agent[1].
Product Specifications
CAS Number
73-05-2
UNSPSC
12352005
Hazard Statement
H302
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/phentolamine-hydrochloride.html
Purity
99.87
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
OC1=CC=CC(N(CC2=NCCN2)C3=CC=C(C)C=C3)=C1.[H]Cl
Molecular Formula
C17H20ClN3O
Molecular Weight
317.82
Precautions
H302
References & Citations
[1]P A Majid, et al. Phentolamine for vasodilator treatment of severe heart-failure. Lancet. 1971 Oct 2;2 (7727) :719-24.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Insect Biochem Mol Biol. 2025 May:180:104312.|bioRxiv. 2023 Oct 13.|J Endocrinol. 2020 Mar;244 (3) :459-471.|J Cancer. 2024 Sep 9;15 (17) :5691-5709.|Neurosci Bull. 2023 Dec;39 (12) :1789-1806.
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