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Phentolamine (hydrochloride)

Phentolamine hydrochloride is an orally active adrenergic α receptor-blocking agent[1].

Product Specifications

CAS Number

[73-05-2]

UNSPSC

12352005

Hazard Statement

H302

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/phentolamine-hydrochloride.html

Purity

99.87

Solubility

DMSO : 116.67 mg/mL (ultrasonic)

Smiles

OC1=CC=CC(N(CC2=NCCN2)C3=CC=C(C)C=C3)=C1.[H]Cl

Molecular Formula

C17H20ClN3O

Molecular Weight

317.82

Precautions

H302

References & Citations

[1]P A Majid, et al. Phentolamine for vasodilator treatment of severe heart-failure. Lancet. 1971 Oct 2;2 (7727) :719-24.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

Launched

Citation 01

Insect Biochem Mol Biol. 2025 May:180:104312.|bioRxiv. 2023 Oct 13.|J Endocrinol. 2020 Mar;244 (3) :459-471.|J Cancer. 2024 Sep 9;15 (17) :5691-5709.|Neurosci Bull. 2023 Dec;39 (12) :1789-1806.

Available Sizes

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