Chondroitinase ABC
Product Specifications
UNSPSC Description
Chondroitinase ABC (ChABC) is an enzyme that degrades glycosaminoglycan side-chains of chondroitin sulfate (CS-GAG) from the chondroitin sulfate proteoglycan (CSPG) core protein. Chondroitinase ABC facilitates reinnervation by degrading CS-GAGs around motoneurons. Chondroitinase ABC has the potential for the research of spinal injury[1][2].
Target Antigen
Endogenous Metabolite
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/chondroitinase-abc.html
Solubility
10 mM in DMSO
Smiles
[Chondroitinase ABC]
References & Citations
[1]Mahajan R, et al. Chondroitinase ABC Enzyme: A Potential Treatment Option for Spinal Cord Injury. Int J Appl Basic Med Res. 2018 Oct-Dec;8(4):203.|[2]Takiguchi M, et al. Chondroitinase ABC Administration Facilitates Serotonergic Innervation of Motoneurons in Rats With Complete Spinal Cord Transection. Front Integr Neurosci. 2022 Jun 30;16:881632.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P2727/Chondroitinase-ABC-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P2727/Chondroitinase-ABC-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
9024-13-9
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