MSDC 0160
MSDC 0160 (Mitoglitazone) is a mitochondrial target of thiazolidinediones (mTOT) -modulating insulin sensitizer and a modulator of mitochondrial pyruvate carrier (MPC) . MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective activities. MSDC 0160 has the potential for Alzheimer′s disease[1][2].
Product Specifications
CAS Number
146062-49-9
Product Name Alternative
Mitoglitazone; CAY10415
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Insulin Receptor; Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/MSDC_0160.html
Purity
99.37
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
O=C(N1)SC(CC2=CC=C(OCC(C3=NC=C(CC)C=C3)=O)C=C2)C1=O
Molecular Formula
C19H18N2O4S
Molecular Weight
370.42
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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TRIAD3A (E3 Ubiquitin Ligase TRIAD3A, E3 ubiquitin-protein ligase RNF216, RING finger protein 216, Ubiquitin-conjugating enzyme 7-interacting protein 1, UbcM4-interacting protein 83, Triad domain-containing protein 3, Rnf216, Triad3, Ubce7ip1, Uip83, Zin)
