IL17A-IN-1
IL17A-IN-1 (compound 72) is an orally active Interleukin 17A inhibitor. IL17A-IN-1 can be used in the study of inflammatory and autoimmune diseases (plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis, etc.), as well as cancer[1].
Product Specifications
UNSPSC
12352005
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/il17a-in-1.html
Solubility
10 mM in DMSO
Smiles
CN1CCC(N2CC3=NC([C@H](C)NC([C@@]4(NC(C5=CC(Cl)=C(Cl)N5)=O)C[C@H](OC4)C6=CC=CC=C6)=O)=NC=C3C2)CC1
Molecular Formula
C30H35Cl2N7O3
Molecular Weight
612.55
References & Citations
[1]Ramos AL, et al. Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds. J Med Chem. 2024 Apr 4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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