Anti-inflammatory agent 38

Anti-inflammatory agent 38 (compound 23d) is a potent Nrf2/HO-1 pathway inhibitor, with an IC50 value of 0.38 μM for NO. Anti-inflammatory agent 38 can significantly reduce the level of ROS in cells. Anti-inflammatory agent 38 can be used for researching anti-inflammatory[1].

Product Specifications

CAS Number

[3032633-42-1]

UNSPSC

12352005

Target

NO Synthase; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-38.html

Purity

98.66

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=S(C1=[N+]([O-])ON=C1OCCOCCOC(CCC(O[C@H]([C@]2([H])[C@@](C[C@H](C)[C@@H]2O)(O)C(/C(C)=C/[C@](C3(C)C)([H])[C@]3([H])CC4)=O)C4=C)=O)=O)(C5=CC=CC=C5)=O

Molecular Formula

C36H46N2O13S

Molecular Weight

746.82

References & Citations

[1]Wang W, et al. Synthesis of lathyrane diterpenoid nitrogen-containing heterocyclic derivatives and evaluation of their anti-inflammatory activities. Bioorg Med Chem.