(S) -Dexfadrostat
(S) -Dexfadrostat ((S) -Fadrozole) is an aromatase inhibitor with an IC50 of 4.6 nM in human placental microsomes in vitro. (S) -Dexfadrostat can be used in the study of estrogen-dependent breast cancer, gynecomastia, and systemic lupus erythematosus[1].
Product Specifications
CAS Number
102676-86-8
Product Name Alternative
(S) -Fadrozole; (S) -CGS 16949A (free base) ; (S) -FAD286
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer; Endocrinology; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/s-dexfadrostat.html
Solubility
DMSO : ≥ 110 mg/mL
Smiles
N#CC1=CC=C([C@@H]2CCCC3=CN=CN23)C=C1
Molecular Formula
C14H13N3
Molecular Weight
223.27
References & Citations
[1]Nancy M; et al. Treating estrogen-dependent diseases with (-) -fadrozole. WO1995028156A1. 1995-04-11
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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