Purified Anti-Mouse Ly6A/E Antibody[D7]
Product Specifications
Background
Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI) -linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.
Abbreviation
Ly6A/E
UniProt
P05533
Host
Rat
Reactivity
Mouse
Immunogen
Recombinant Mouse Ly6A/E protein
Target
SCA; Ly-6A2/Ly-6E; Ly-6A.2/Ly-6E.1; SCA-1; TAP; Ly6; Ly6a
Clonality
Monoclonal
Clone
D7
Conjugation
Unconjugated
Applications
FCM
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Rat IgG2a, κ
Available Sizes
Curated Selection
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