Hexyl gallate
Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) shows antibacterial activity and inhibits the production of rhamnolipid and pyocyanin by inhibiting RhlR[1]. Hexyl gallate, a alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum, with IC50 of 0.11 mM[2].
Product Specifications
CAS Number
1087-26-9
Product Name Alternative
Hexyl 3,4,5-trihydroxybenzoate
UNSPSC
12352005
Hazard Statement
H302, H317
Target
Bacterial; Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hexyl-gallate.html
Concentration
10mM
Purity
99.75
Solubility
DMSO : 41.67 mg/mL (ultrasonic)
Smiles
O=C(OCCCCCC)C1=CC(O)=C(O)C(O)=C1
Molecular Formula
C13H18O5
Molecular Weight
254.28
Precautions
H302, H317
References & Citations
[1]Ade Arsianti, et al. Synthesis and in vitro antimalarial activity of alkyl esters of gallate as a growth inhibitor of plasmodium falciparum. Oriental Journal of Chemistry, 34 (2), 655-662.|[2]Kim B, et al. Differential effects of alkyl gallates on quorum sensing in Pseudomonas aeruginosa. Sci Rep. 2019;9 (1) :7741. Published 2019 May 23.|[3]Cavalca LB, et al. Hexyl gallate for the control of citrus canker caused by Xanthomonas citri subsp citri [published online ahead of print, 2020 Aug 6]. Microbiologyopen. 2020; e1104.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
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