Hexyl gallate

Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) shows antibacterial activity and inhibits the production of rhamnolipid and pyocyanin by inhibiting RhlR[1]. Hexyl gallate, a alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum, with IC50 of 0.11 mM[2].

Product Specifications

CAS Number

[1087-26-9]

Product Name Alternative

Hexyl 3,4,5-trihydroxybenzoate

UNSPSC

12352005

Hazard Statement

H302, H317

Target

Bacterial; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hexyl-gallate.html

Concentration

10mM

Purity

99.75

Solubility

DMSO : 41.67 mg/mL (ultrasonic)

Smiles

O=C(OCCCCCC)C1=CC(O)=C(O)C(O)=C1

Molecular Formula

C13H18O5

Molecular Weight

254.28

Precautions

H302, H317

References & Citations

[1]Ade Arsianti, et al. Synthesis and in vitro antimalarial activity of alkyl esters of gallate as a growth inhibitor of plasmodium falciparum. Oriental Journal of Chemistry, 34 (2), 655-662.|[2]Kim B, et al. Differential effects of alkyl gallates on quorum sensing in Pseudomonas aeruginosa. Sci Rep. 2019;9 (1) :7741. Published 2019 May 23.|[3]Cavalca LB, et al. Hexyl gallate for the control of citrus canker caused by Xanthomonas citri subsp citri [published online ahead of print, 2020 Aug 6]. Microbiologyopen. 2020; e1104.