Perfluorohexane sulfonamide

Perfluorohexane sulfonamide (FHxSA) is the inhibitor for carbonic anhydrase, that inhibits bovine CA and human CA II with IC50 of 0.122 and 1.38 μM. Perfluorohexane sulfonamide is a delayed-action insecticide, that can be used to control red fire ants (Solenopsis invicta) . Perfluorohexane sulfonamide could be a environmental pollutant[1][2][3].

Product Specifications

CAS Number

[41997-13-1]

Product Name Alternative

FHxSA

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Purity

81.50

Smiles

O=S(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)(N)=O

Molecular Formula

C6H2F13NO2S

Molecular Weight

399.13

Precautions

H315, H319, H335

References & Citations

[1]D'Agostino LA, et al., Certain Perfluoroalkyl and Polyfluoroalkyl Substances Associated with Aqueous Film Forming Foam Are Widespread in Canadian Surface Waters. Environ Sci Technol. 2017 Dec 5;51 (23) :13603-13613. |[2]Benfodda Z, et al., Synthesis and investigation of inhibition effect of fluorinated sulfonamide derivatives on carbonic anhydrase. Eur J Med Chem. 2010 Mar;45 (3) :1225-9. |[3]Vander Meer RK, et al., Fluoroaliphatic sulfones: a new class of delayed-action insecticides for control of Solenopsis invicta (Hymenoptera: Formicidae) . J Econ Entomol. 1985 Dec;78 (6) :1190-7.