MTH1 ligand 1
MTH1 ligand 1 is a target protein ligand for MTH1 and can be used to synthesize PROTAC aTAG 2139 (HY-161162) [1].
Product Specifications
CAS Number
[2412986-35-5]
UNSPSC
12352005
Target
DNA/RNA Synthesis; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mth1-ligand-1.html
Smiles
O=C(C1=NC=C(C2=CC=C3N=CC(C(NC)=O)=C(NC4=CC=CC=C4)C3=C2)C=C1)O
Molecular Formula
C23H18N4O3
Molecular Weight
398.41
References & Citations
[1]Gesine K. Veits, et al. Development of an AchillesTAG degradation system and its application to control CAR-T activity. Current Research in Chemical Biology Volume 1, 2021, 100010
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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