Melilotic acid

Melilotic acid (3- (2-hydroxyphenyl) -propanoic acid) is an orally active compound. Melilotic acid can be isolated from the bark of Chinese cinnamon. Melilotic acid has a significant inhibitory effect on gastric ulcers induced by serotonin (HY-B1473A), phenylbutazone (HY-B0230), ethanoyl, and water immersion stress[1][2].

Product Specifications

CAS Number

[495-78-3]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/melilotic-acid.html

Concentration

10mM

Purity

99.97

Solubility

DMSO : 200 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

O=C(O)CCC1=CC=CC=C1O

Molecular Formula

C9H10O3

Molecular Weight

166.18

Precautions

H315, H319, H335

References & Citations

[1]LEVY CC, et al. THE METABOLISM OF COUMARIN BY A MICROORGANISM. II. THE REDUCTION OF O-COUMARIC ACID TO MELILOTIC ACID. Biochemistry. 1964 Dec;3:1944-7. |[2]Tanaka S, et al. Antiulcerogenic compounds isolated from Chinese cinnamon. Planta Med. 1989 Jun;55 (3) :245-8.