Sirolimus BSA Conjugate Solution

<strong>Sirolimus BSA Conjugate</strong>_x000D_ <table width="643">_x000D_ <tbody>_x000D_ <tr>_x000D_ <td>Catalog number:</td>_x000D_ <td>P2010025</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Lot number:</td>_x000D_ <td>Batch Dependent</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Expiration date:</td>_x000D_ <td>Batch Dependent</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Purity:</td>_x000D_ <td>&gt; 95%</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Concentration:</td>_x000D_ <td>1 mg/mL</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Package Size:</td>_x000D_ <td>0.5 mg</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Molecular Weight:</td>_x000D_ <td>71 kDa (average)</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Storage:</td>_x000D_ <td>-20°C. Avoid repeated freeze/thaw cycles.</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Other names:</td>_x000D_ <td>BSA-Sirolimus, Sirolimus-BSA, BSA conjugated to Sirolimus, Sirolimus Bovine Serum Albumin Conjugate, Sirolimus [BSA], BSA- Rapamycin, Rapamycin -BSA, BSA conjugated to Rapamycin, Rapamycin Bovine Serum Albumin Conjugate, Rapamycin [BSA]</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Keywords:</td>_x000D_ <td>BSA conjugate, Sirolimus, (-)-Rapamycin; Rapamycin; Sirolimús; Sirolimusum</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Buffer:</td>_x000D_ <td>1X Phosphate Buffer Saline, pH 7.4.</td>_x000D_ </tr>_x000D_ </tbody>_x000D_ </table>_x000D_ <strong>About Sirolimus</strong>_x000D_ _x000D_ Also known as Rapamycin, Sirolimus is a cyclic macrolide naturally produced by a strain of <em>Streptomyces hygroscopicus. </em>The name Rapamycin derives from the name of the island where the fungus was first isolated: Rapa Nui, also known as Easter Island. Sirolimus originally exhibited antifungal activities and later found to have immunosuppressive and antitumor activities. Sirolimus inhibits the production of cyotkines by blocking the transcriptional activation of cytokine genes._x000D_ _x000D_ <a href="https://moleculardepot.com/wp-content/uploads/2021/09/MKT-008-Tacrolimus-Brochure.pdf"><strong>Complete Tacrolimus Product Line</strong></a>_x000D_ _x000D_ <a href="https://moleculardepot.com/wp-content/uploads/2021/09/MKT-008-Tacrolimus-Brochure.pdf">Download Brochure</a>_x000D_ _x000D_ <a href="https://moleculardepot.com/wp-content/uploads/2021/09/MKT-008-Tacrolimus-Brochure.pdf"><img class="media-library__list-item-centered is-image" draggable="false" src="https://i0.wp.com/moleculardepot.com/wp-content/uploads/2019/02/cropped-LogoHD-3.png?ssl=1&amp;resize=438,438" alt="cropped-LogoHD-3.png" width="94" height="94" /></a>_x000D_ _x000D_ <strong>References</strong>_x000D_ <ul>_x000D_ <li>Pritchard DI: Sourcing a chemical succession for cyclosporin from parasites and human pathogens. <a href="https://www.ncbi.nlm.nih.gov/pubmed/15896681">Drug Discov Today</a>. 2005 May 15;10(10):688-91.</li>_x000D_ <li>Shuchman M: Trading restenosis for thrombosis? New questions about drug-eluting stents. N Engl J Med. 2006 Nov 9;355(19):1949-52.</li>_x000D_ <li>Sun SY, Rosenberg LM, Wang X, Zhou Z, Yue P, Fu H, Khuri FR: Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition. Cancer Res. 2005 Aug 15;65(16):7052-8.</li>_x000D_ <li>Chan S: Targeting the mammalian target of rapamycin (mTOR): a new approach to treating cancer. Br J Cancer. 2004 Oct 18;91(8):1420-4.</li>_x000D_ <li>Graziani EI: Recent advances in the chemistry, biosynthesis and pharmacology of rapamycin analogs. Nat Prod Rep. 2009 May;26(5):602-9.</li>_x000D_ <li>Lv X, Qi J, Zhou M, Shi B, Cai C, Tang Y, Pan T, Han Y. Comparative efficacy of 20 graft-versus-host disease prophylaxis therapies for patients after hematopoietic stem-cell transplantation: A multiple-treatments network meta-analysis. <span class="jrnl" title="Critical reviews in oncology/hematology">Crit Rev Oncol Hematol</span>. 2020 Mar 20;150:102944.</li>_x000D_ </ul>_x000D_ <strong>Related Products</strong>_x000D_ _x000D_ https://moleculardepot.com/product/everolimus-bsa-conjugate/_x000D_ _x000D_ https://moleculardepot.com/product/tacrolimus-bsa-conjugate-p2010001/