C12-NBD-ceramide
C12-NBD-ceramide is a fluorescent analogue of ceramide, it can be used as a substrate in ceramidase assays[1][2].
Product Specifications
CAS Number
[202850-01-9]
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/c12-nbd-ceramide.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(CCCCCCCCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C12)=O
Molecular Formula
C36H61N5O6
Molecular Weight
659.90
References & Citations
[1]Tani M, et al. Specific and sensitive assay for alkaline and neutral ceramidases involving C12-NBD-ceramide. J Biochem. 1999 Apr;125 (4) :746-9.|[2]Otsuka Y, et al. Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening. SLAS Discov. 2021 Jan;26 (1) :113-121.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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