C12-NBD-ceramide

C12-NBD-ceramide is a fluorescent analogue of ceramide, it can be used as a substrate in ceramidase assays[1][2].

Product Specifications

CAS Number

[202850-01-9]

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/c12-nbd-ceramide.html

Solubility

10 mM in DMSO

Smiles

CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(CCCCCCCCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C12)=O

Molecular Formula

C36H61N5O6

Molecular Weight

659.90

References & Citations

[1]Tani M, et al. Specific and sensitive assay for alkaline and neutral ceramidases involving C12-NBD-ceramide. J Biochem. 1999 Apr;125 (4) :746-9.|[2]Otsuka Y, et al. Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening. SLAS Discov. 2021 Jan;26 (1) :113-121.