Tafetinib analogue 1

Tafetinib (SIM010603) analogue 1 is an analog of the tyrosine kinase receptor inhibitor Tafetinib (SIM010603) .[1].

Product Specifications

CAS Number

[1032265-67-0]

Product Name Alternative

SIM010603 analogue 1

UNSPSC

12352005

Target

C-Kit; RET; VEGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tafetinib-analogue-1.html

Smiles

O=C(NCCN(C)C)C1=C(NC2=C1CCC/C2=C3C(NC4=C/3C=C(C=C4)F)=O)C

Molecular Formula

C22H25FN4O2

Molecular Weight

396.46

References & Citations

[1]Mao Y, et al. Evaluation of subchronic toxicity of SIM010603, a potent inhibitor of receptor tyrosine kinase, after 28-day repeated oral administration in SD rats and beagle dogs. Food Chem Toxicol. 2012 May;50 (5) :1256-70.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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