Tafetinib analogue 1
Tafetinib (SIM010603) analogue 1 is an analog of the tyrosine kinase receptor inhibitor Tafetinib (SIM010603) .[1].
Product Specifications
CAS Number
[1032265-67-0]
Product Name Alternative
SIM010603 analogue 1
UNSPSC
12352005
Target
C-Kit; RET; VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tafetinib-analogue-1.html
Smiles
O=C(NCCN(C)C)C1=C(NC2=C1CCC/C2=C3C(NC4=C/3C=C(C=C4)F)=O)C
Molecular Formula
C22H25FN4O2
Molecular Weight
396.46
References & Citations
[1]Mao Y, et al. Evaluation of subchronic toxicity of SIM010603, a potent inhibitor of receptor tyrosine kinase, after 28-day repeated oral administration in SD rats and beagle dogs. Food Chem Toxicol. 2012 May;50 (5) :1256-70.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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