MK-212 (monohydrochloride)
MK-212 (CPP) monohydrochloride is a centrally acting 5-HT1C/5-HT2 agonist. MK-212 monohydrochloride can stimulate phosphoinositide hydrolysis in cerebral cortex[1].
Product Specifications
CAS Number
[61655-58-1]
Product Name Alternative
CPP (monohydrochloride)
UNSPSC
12352005
Hazard Statement
H301
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mk-212-monohydrochloride.html
Purity
99.69
Solubility
H2O : 10 mg/mL (ultrasonic)
Smiles
ClC1=NC(N2CCNCC2)=CN=C1.Cl
Molecular Formula
C8H12Cl2N4
Molecular Weight
235.12
Precautions
H301
References & Citations
[1]Lee HS, et, al. Effect of the serotonin agonist, MK-212, on body temperature in schizophrenia. Biol Psychiatry. 1992 Mar 1;31 (5) :460-70.|[2]Conn PJ, et, al. Relative efficacies of piperazines at the phosphoinositide hydrolysis-linked serotonergic (5-HT-2 and 5-HT-1c) receptors. J Pharmacol Exp Ther. 1987 Aug;242 (2) :552-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
5-HT1 Receptor; mLAG-3; α-1 microglobulin
Available Sizes
Curated Selection
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