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MK-212 (monohydrochloride)

Product Specifications

UNSPSC Description

MK-212 (CPP) monohydrochloride is a centrally acting 5-HT1C/5-HT2 agonist. MK-212 monohydrochloride can stimulate phosphoinositide hydrolysis in cerebral cortex[1].

Target Antigen

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mk-212-monohydrochloride.html

Purity

99.62

Solubility

H2O : 10 mg/mL (ultrasonic)

Smiles

ClC1=NC(N2CCNCC2)=CN=C1.Cl

Molecular Weight

235.118

References & Citations

[1]Lee HS, et, al. Effect of the serotonin agonist, MK-212, on body temperature in schizophrenia. Biol Psychiatry. 1992 Mar 1;31(5):460-70.|[2]Conn PJ, et, al. Relative efficacies of piperazines at the phosphoinositide hydrolysis-linked serotonergic (5-HT-2 and 5-HT-1c) receptors. J Pharmacol Exp Ther. 1987 Aug;242(2):552-7.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-101324A/MK-212-monohydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-101324A/MK-212-monohydrochloride-SDS-MedChemExpress.pdf

Clinical Information

Phase 3

CAS Number

61655-58-1

Available Sizes

Curated Selection

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