MK-212 (monohydrochloride)
Product Specifications
UNSPSC Description
MK-212 (CPP) monohydrochloride is a centrally acting 5-HT1C/5-HT2 agonist. MK-212 monohydrochloride can stimulate phosphoinositide hydrolysis in cerebral cortex[1].
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mk-212-monohydrochloride.html
Purity
99.62
Solubility
H2O : 10 mg/mL (ultrasonic)
Smiles
ClC1=NC(N2CCNCC2)=CN=C1.Cl
Molecular Weight
235.118
References & Citations
[1]Lee HS, et, al. Effect of the serotonin agonist, MK-212, on body temperature in schizophrenia. Biol Psychiatry. 1992 Mar 1;31(5):460-70.|[2]Conn PJ, et, al. Relative efficacies of piperazines at the phosphoinositide hydrolysis-linked serotonergic (5-HT-2 and 5-HT-1c) receptors. J Pharmacol Exp Ther. 1987 Aug;242(2):552-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101324A/MK-212-monohydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101324A/MK-212-monohydrochloride-SDS-MedChemExpress.pdf
Clinical Information
Phase 3
CAS Number
61655-58-1
Available Sizes
Curated Selection
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