MK-212 (monohydrochloride)

MK-212 (CPP) monohydrochloride is a centrally acting 5-HT1C/5-HT2 agonist. MK-212 monohydrochloride can stimulate phosphoinositide hydrolysis in cerebral cortex[1].

Product Specifications

CAS Number

[61655-58-1]

Product Name Alternative

CPP (monohydrochloride)

UNSPSC

12352005

Hazard Statement

H301

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mk-212-monohydrochloride.html

Purity

99.69

Solubility

H2O : 10 mg/mL (ultrasonic)

Smiles

ClC1=NC(N2CCNCC2)=CN=C1.Cl

Molecular Formula

C8H12Cl2N4

Molecular Weight

235.12

Precautions

H301

References & Citations

[1]Lee HS, et, al. Effect of the serotonin agonist, MK-212, on body temperature in schizophrenia. Biol Psychiatry. 1992 Mar 1;31 (5) :460-70.|[2]Conn PJ, et, al. Relative efficacies of piperazines at the phosphoinositide hydrolysis-linked serotonergic (5-HT-2 and 5-HT-1c) receptors. J Pharmacol Exp Ther. 1987 Aug;242 (2) :552-7.