2,3-Diphosphoglyceric acid (pentasodium)

2,3-Diphosphoglyceric acid (2,3-DPG) pentasodium is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid pentasodium stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2,3-Diphosphoglyceric acid pentasodium binds to hemoglobin and decrease its affinity for oxygen[1][2].

Product Specifications

CAS Number

[1287756-01-7]

Product Name Alternative

2,3-DPG (pentasodium)

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Parasite

Type

Natural Products

Related Pathways

Anti-infection

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-3-diphosphoglyceric-acid-pentasodium.html

Purity

98.0

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : ≥ 200 mg/mL

Smiles

O=C(O[Na])C(OP(O[Na])(O[Na])=O)COP(O[Na])(O[Na])=O

Molecular Formula

C3H3Na5O10P2

Molecular Weight

375.95

Precautions

H302, H315, H319, H335

References & Citations

[1]Shakil H. Merchant MD, et al. 24 - Molecular Diagnosis in Hematopathology. Hematopathology (Second Edition) .2012, 679-726. |[2]Płoszczyca K, et al. Red Blood Cell 2,3-Diphosphoglycerate Decreases in Response to a 30 km Time Trial Under Hypoxia in Cyclists. Front Physiol. 2021 Jun 15;12:670977.