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Tyloxapol

Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surface active stabilizer. Tyloxapol is used to induce hyperlipidemia in animals[1][2].

Product Specifications

CAS Number

[25301-02-4]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Tyloxapol.html

Purity

0

Solubility

DMSO : ≥ 38 mg/mL|Ethanol : 100 mg/mL (ultrasonic) |H2O : 120 mg/mL (ultrasonic)

Smiles

[H]OCCOC1=C(CC)C=C(C(CC(C)(C)C)(C)C)C=C1C.[6].[=].[<].[5].[8].[n].[m].[_].[=].[m].[n]

Molecular Formula

(C15H21O (C2H4O) m) n

Molecular Weight

261.38 (monomer)

Precautions

H315, H319, H335

References & Citations

[1]Heba Mohamed Abdou, et al. The Journal of Basic and Applied Zoology volume 79, Article number: 51 (2018) .|[2]de Sousa JA, et al. Evaluation of DNA damage in Wistar rat tissues with hyperlipidemia induced by tyloxapol. Exp Mol Pathol. 2017 Aug;103 (1) :51-55.|[3]Julijana Kristl, et al. Surface active stabilizer tyloxapol in colloidal dispersions exerts cytostatic effects and apoptotic dismissal of cells. Toxicol Appl Pharmacol. 2008 Oct 15;232 (2) :218-25.|[4]Kuroda M, et al. Biochim Biophys Acta. 1977 Oct 24;489 (1) :119-25.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Curated Selection

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