Bevurogant
Bevurogant (BI 730357) is a retinoid-related orphan receptor-gamma t (RORγt) antagonist. Bevurogant can be used for the research of chronic inflammatory diseases[1].
Product Specifications
CAS Number
[1817773-66-2]
Product Name Alternative
BI 730357
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
ROR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bevurogant.html
Purity
99.54
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
C[C@@H](C1CC1)N2C3=NC(C4=C(C)N=CN=C4C5CC5)=NC=C3N=C(C2=O)NCC6=CC=C(C=N6)S(C)(=O)=O
Molecular Formula
C26H28N8O3S
Molecular Weight
532.62
Precautions
H302, H315, H319, H335
References & Citations
[1]BAKONYI J, et, al. Compounds as modulators of ror gamma. US20150291607A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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