AChE/BChE-IN-19
AChE/BChE-IN-19 (Compound 12) is a nicotinic hydrazide derivative. AChE/BChE-IN-19 is a inhibitor of AChE (IC50 = 21.45 nM) and BChE (IC50 =18.42 nM) . AChE/BChE-IN-19 can be used in Alzheimer's disease research[1].
Product Specifications
CAS Number
3036136-22-5
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-bche-in-19.html
Solubility
10 mM in DMSO
Smiles
O=C(N/N=C/C1=C(C=CC=C2)C2=CC=C1OC(C3=CC=C(N(C)C)C=C3)=O)C4=CN=CC=C4
Molecular Formula
C26H22N4O3
Molecular Weight
438.48
References & Citations
[1]Resiţ Çakmak, et al. Synthesis of Novel Hydrazide−Hydrazone Compounds and In Vitro and In Silico Investigation of Their Biological Activities against AChE, BChE, and hCA I and II. ACS Omega. 2024, 9, 18, 20030–20041
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE
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