CHIR-2279
CHIR-2279 is a high-affinity ligand (Ki=5 nM) for the α1-adrenergic receptor and can be further studied as a drug lead compound[1].
Product Specifications
CAS Number
[158198-45-9]
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/chir-2279.html
Smiles
O=C(CN(CCC1=CC=CC=C1)C(CN(C(CNCCC2=CC=C(C=C2)O)=O)C3=CC=C(C4=CC=CC=C4)C=C3)=O)N
Molecular Formula
C34H36N4O4
Molecular Weight
564.67
References & Citations
[1]Zuckermann, et al. Discovery of nanomolar ligands for 7-transmembrane G-protein-coupled receptors from a diverse N- (substituted) glycine peptoid library. Journal of medicinal chemistry 37.17 (1994) : 2678-2685.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α adrenergic receptor
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