PGDM

PGDM (Prostaglandin D Metabolite) is the main urinary metabolite of Prostaglandin D2 and is prone to reversible cyclization. PGDM may serve as a biomarker for the endogenous production of PGD2 or be used to evaluate the severity of acute allergic reactions[1].

Product Specifications

CAS Number

[133161-96-3]

Product Name Alternative

Prostaglandin D Metabolite

UNSPSC

12352211

Hazard Statement

H225-H319-H336

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/pgdm.html

Solubility

10 mM in DMSO

Smiles

OC(CCC(CC[C@@H]1[C@H]([C@H](C[C@@H]1O)O)C/C=C\CC(O)=O)=O)=O

Molecular Formula

C16H24O7

Molecular Weight

328.36

Precautions

P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Inagaki S, et al. Urinary PGDM, a prostaglandin D2 metabolite, is a novel biomarker for objectively detecting allergic reactions of food allergy. J Allergy Clin Immunol. 2018 Nov;142 (5) :1634-1636.e10.