Ac-LETD-AFC
Ac-LETD-AFC is a caspase-8 fluorogenic substrate. Ac-LETD-AFC can measure caspase-8 fluorogenic activity and can be used for the research of cancer cell apoptosis and oxidative stress metabolism[1].
Product Specifications
CAS Number
210345-02-1
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ac-letd-afc.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C(C(C(O1)=C2)=CC=C2NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC(C)C)=O)=O)=O)=O)=CC1=O)F
Molecular Formula
C31H38F3N5O12
Molecular Weight
729.65
References & Citations
[1]Ignacio Bejarano, et al. Melatonin enhances hydrogen peroxide-induced apoptosis in human promyelocytic leukaemia HL-60 cells. Mol Cell Biochem. 2011 Jul;353 (1-2) :167-76.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K7369106 1.0 µg DNA
Tubb2c sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
Sign In for Pricing
View Details 
MBS2904123-01 48 Well
Rat Trpm2/Transient receptor potential cation channel subfamily M member 2 ELISA Kit
Sign In for Pricing
View Details MBS2904123-02 96 Well
Rat Trpm2/Transient receptor potential cation channel subfamily M member 2 ELISA Kit
Sign In for Pricing
View Details MBS2904123-03 5x 96 Well
Rat Trpm2/Transient receptor potential cation channel subfamily M member 2 ELISA Kit
Sign In for Pricing
View Details MBS2904123-04 10x 96 Well
Rat Trpm2/Transient receptor potential cation channel subfamily M member 2 ELISA Kit
Sign In for Pricing
View Details 
GTR15284447 1 Vial
Lentiviral mouse 4933416I08Rik shRNA (UAS) - Lentiviral mouse 4933416I08Rik shRNA (UAS, RFP) (25)
Sign In for Pricing
View Details