Ac-LETD-AFC

Ac-LETD-AFC is a caspase-8 fluorogenic substrate. Ac-LETD-AFC can measure caspase-8 fluorogenic activity and can be used for the research of cancer cell apoptosis and oxidative stress metabolism[1].

Product Specifications

CAS Number

[210345-02-1]

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ac-letd-afc.html

Solubility

10 mM in DMSO

Smiles

FC(F)(C(C(C(O1)=C2)=CC=C2NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC(C)C)=O)=O)=O)=O)=CC1=O)F

Molecular Formula

C31H38F3N5O12

Molecular Weight

729.65

References & Citations

[1]Ignacio Bejarano, et al. Melatonin enhances hydrogen peroxide-induced apoptosis in human promyelocytic leukaemia HL-60 cells. Mol Cell Biochem. 2011 Jul;353 (1-2) :167-76.