Ac-LETD-AFC
Ac-LETD-AFC is a caspase-8 fluorogenic substrate. Ac-LETD-AFC can measure caspase-8 fluorogenic activity and can be used for the research of cancer cell apoptosis and oxidative stress metabolism[1].
Product Specifications
CAS Number
210345-02-1
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ac-letd-afc.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C(C(C(O1)=C2)=CC=C2NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC(C)C)=O)=O)=O)=O)=CC1=O)F
Molecular Formula
C31H38F3N5O12
Molecular Weight
729.65
References & Citations
[1]Ignacio Bejarano, et al. Melatonin enhances hydrogen peroxide-induced apoptosis in human promyelocytic leukaemia HL-60 cells. Mol Cell Biochem. 2011 Jul;353 (1-2) :167-76.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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