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(E/Z) -Sivopixant

(E/Z) -Sivopixant ((E/Z) -S-600918) is a potent P2X3 receptor antagonist with an IC50 of 4 nM. (E/Z) -Sivopixant can be used for respiratory diseases research[1].

Product Specifications

CAS Number

1640808-39-4

Product Name Alternative

(E/Z) -S-600918

UNSPSC

12352005

Target

P2X Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/e-z-sivopixant.html

Purity

98.64

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N(C1=O)C[C@H](C)C(O)=O)N=C(NC2=CC=C(C=C2)OC3=CC=CC=N3)N1CC4=CC=C(C=C4)Cl

Molecular Formula

C25H22ClN5O5

Molecular Weight

507.93

References & Citations

[1]Kai, Hiroyuki, et al. Amino-triazine derivatives and pharmaceutical composition containing said derivatives. WO2014200078A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

P2X3 Receptor

Available Sizes

Frequently Asked Questions

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