(E/Z) -Sivopixant
(E/Z) -Sivopixant ((E/Z) -S-600918) is a potent P2X3 receptor antagonist with an IC50 of 4 nM. (E/Z) -Sivopixant can be used for respiratory diseases research[1].
Product Specifications
CAS Number
[1640808-39-4]
Product Name Alternative
(E/Z) -S-600918
UNSPSC
12352005
Target
P2X Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/e-z-sivopixant.html
Purity
98.64
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N(C1=O)C[C@H](C)C(O)=O)N=C(NC2=CC=C(C=C2)OC3=CC=CC=N3)N1CC4=CC=C(C=C4)Cl
Molecular Formula
C25H22ClN5O5
Molecular Weight
507.93
References & Citations
[1]Kai, Hiroyuki, et al. Amino-triazine derivatives and pharmaceutical composition containing said derivatives. WO2014200078A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2X3 Receptor
Available Sizes
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