Amorolfine (hydrochloride)
Amorolfine (Ro 14-4767/002) hydrochloride is a potent anti-fungal agent. Amorolfine hydrochloride inhibits ergosterol biosynthesis. Amorolfine hydrochloride has the potential for the research of Neoscytalidium dimidiatum onychomycosis[1][2].
Product Specifications
CAS Number
78613-38-4
Product Name Alternative
Ro 14-4767/002
UNSPSC
12352005
Hazard Statement
H302, H315, H411
Target
Antibiotic; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Amorolfine-hydrochloride.html
Concentration
10mM
Purity
99.84
Solubility
DMSO : 12.5 mg/mL (ultrasonic) |H2O : 3.33 mg/mL (ultrasonic)
Smiles
C[C@@H]1O[C@H](C)CN(CC(C)CC2=CC=C(C(C)(C)CC)C=C2)C1.Cl
Molecular Formula
C21H36ClNO
Molecular Weight
353.97
Precautions
H302, H315, H411
References & Citations
[1]Haria M, et al. Amorolfine. A review of its pharmacological properties and therapeutic potential in the treatment of onychomycosis and other superficial fungal infections. Drugs. 1995 Jan;49 (1) :103-20.|[2]Bunyaratavej S, et al. Efficacy of 5% amorolfine nail lacquer in Neoscytalidium dimidiatum onychomycosis. J Dermatolog Treat. 2016 Aug;27 (4) :359-63.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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