Amorolfine (hydrochloride)

Amorolfine (Ro 14-4767/002) hydrochloride is a potent anti-fungal agent. Amorolfine hydrochloride inhibits ergosterol biosynthesis. Amorolfine hydrochloride has the potential for the research of Neoscytalidium dimidiatum onychomycosis[1][2].

Product Specifications

CAS Number

[78613-38-4]

Product Name Alternative

Ro 14-4767/002

UNSPSC

12352005

Hazard Statement

H302, H315, H411

Target

Antibiotic; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Amorolfine-hydrochloride.html

Concentration

10mM

Purity

99.84

Solubility

DMSO : 12.5 mg/mL (ultrasonic) |H2O : 3.33 mg/mL (ultrasonic)

Smiles

C[C@@H]1O[C@H](C)CN(CC(C)CC2=CC=C(C(C)(C)CC)C=C2)C1.Cl

Molecular Formula

C21H36ClNO

Molecular Weight

353.97

Precautions

H302, H315, H411

References & Citations

[1]Haria M, et al. Amorolfine. A review of its pharmacological properties and therapeutic potential in the treatment of onychomycosis and other superficial fungal infections. Drugs. 1995 Jan;49 (1) :103-20.|[2]Bunyaratavej S, et al. Efficacy of 5% amorolfine nail lacquer in Neoscytalidium dimidiatum onychomycosis. J Dermatolog Treat. 2016 Aug;27 (4) :359-63.