Conjugated (9Z,11E) -Linoleic Acid

<strong>Conjugated (9Z,11E)-Linoleic Acid</strong>_x000D_ <strong>Catalog number:</strong> B2018088_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 25 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 280.45_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20℃_x000D_ <strong>Keywords:</strong> (9Z,11E)-9,11-Octadecadienoic acid, 9Z,11E-CLA, Bovinic acid, Linoleic acid (9-cis, 11-trans)_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Chen CA, Lu W, Sih CJ. Synthesis of 9Z,11E-octadecadienoic and 10E,12Z-octadecadienoic acids, the major components of conjugated linoleic acid Lipids. 1999 Aug;34(8):879-84._x000D_ 2: Lee Y. Isomer specificity of conjugated linoleic acid (CLA): 9E,11E-CLA Nutr Res Pract. 2008 Winter;2(4):326-30._x000D_ 3: Smith GN, Taj M, Braganza JM. On the identification of a conjugated diene component of duodenal bile as 9Z,11E-octadecadienoic acid Free Radic Biol Med. 1991;10(1):13-21._x000D_ 4: Moya-Camarena SY, Vanden Heuvel JP, Blanchard SG, Leesnitzer LA, Belury MA. Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPARalpha J Lipid Res. 1999 Aug;40(8):1426-33._x000D_ 5: Lee Y, Thompson JT, de Lera AR, Vanden Heuvel JP. Isomer-specific effects of conjugated linoleic acid on gene expression in RAW 264.7 J Nutr Biochem. 2009 Nov;20(11):848-59, 859.e1-5._x000D_ 6: Li Z, Tran VH, Duke RK, Ng MC, Yang D, Duke CC. Synthesis and biological activity of hydroxylated derivatives of linoleic acid and conjugated linoleic acids Chem Phys Lipids. 2009 Mar;158(1):39-45._x000D_ 7: Hwang DM, Kundu JK, Shin JW, Lee JC, Lee HJ, Surh YJ. cis-9,trans-11-conjugated linoleic acid down-regulates phorbol ester-induced NF-kappaB activation and subsequent COX-2 expression in hairless mouse skin by targeting IkappaB kinase and PI3K-Akt Carcinogenesis. 2007 Feb;28(2):363-71._x000D_ 8: Lampen A, Leifheit M, Voss J, Nau H. Molecular and cellular effects of cis-9, trans-11-conjugated linoleic acid in enterocytes: effects on proliferation, differentiation, and gene expression Biochim Biophys Acta. 2005 Jun 15;1735(1):30-40._x000D_ 9: Huyan Z, Pellegrini N, Steegenga W, Capuano E. Insights into gut microbiota metabolism of dietary lipids: the case of linoleic acid Food Funct. 2022 Apr 20;13(8):4513-4526._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/9989264">10: Moya-Camarena SY, Van den Heuvel JP, Belury MA. Conjugated linoleic acid activates peroxisome proliferator-activated receptor alpha and beta subtypes but does not induce hepatic peroxisome proliferation in Sprague-Dawley rats Biochim Biophys Acta. 1999 Jan 4;1436(3):331-42. </a>_x000D_ _x000D_ <strong>Products Related to Conjugated (9Z,11E)-Linoleic Acid can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals /"> Chemicals </a>