Human DLL3 (353-492) Protein, His Tag
Human DLL3 (353-492), His Tag (DL3-H52Ha) is expressed from human 293 cells (HEK293) . It contains AA Arg 353 - Leu 492 (Accession # Q9NYJ7-1) .
Product Specifications
Background
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.4 kDa. The protein migrates as 18 kDa and 19-21 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
Q9NYJ7-1
Expression Region
Arg 353 - Leu 492
Host
HEK293
Target
DLL3
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Immobilized Human DLL3 (353-492) , His Tag (Cat. No. DL3-H52Ha) at 1 μg/mL (100 μL/well) can bind Anti-DLL3 Antibody (specific Binding EGFs of DLL3), Human IgG1 with a linear range of 0.1-2 ng/mL (QC tested).
Format
Liquid
Buffer
PBS, 0.5 M Arginine, pH7.4
Molecular Weight
16.4 kDa
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
1mg*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/DL3-H52Ha.pdf
Species
Human
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