L-CCG-I
L-CCG-I is an extended isomer of conformationally restricted glutamate analog. L-CCG-I also is a potent agonist for mGluR2 with an EC50 value of 0.3 nM. L-CCG-I can be used for the research of mGluR family[1].
Product Specifications
CAS Number
117857-93-9
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-ccg-i.html
Solubility
10 mM in DMSO
Smiles
[H][C@@]1([C@H](N)C(O)=O)[C@@H](C(O)=O)C1
Molecular Formula
C6H9NO4
Molecular Weight
159.14
Precautions
H302, H315, H319, H335
References & Citations
[1]Y Hayashi, et al. Agonist analysis of 2- (carboxycyclopropyl) glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells. Br J Pharmacol. 1992 Oct;107 (2) :539-43.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR2
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