L-CCG-I

L-CCG-I is an extended isomer of conformationally restricted glutamate analog. L-CCG-I also is a potent agonist for mGluR2 with an EC50 value of 0.3 nM. L-CCG-I can be used for the research of mGluR family[1].

Product Specifications

CAS Number

[117857-93-9]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/l-ccg-i.html

Solubility

10 mM in DMSO

Smiles

[H][C@@]1([C@H](N)C(O)=O)[C@@H](C(O)=O)C1

Molecular Formula

C6H9NO4

Molecular Weight

159.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Y Hayashi, et al. Agonist analysis of 2- (carboxycyclopropyl) glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells. Br J Pharmacol. 1992 Oct;107 (2) :539-43.