BITC-SG
BITC-SG is the conjugate of phenylisothiocyanate (BITC) and glutathione (GSH) . BITC-SG is involved in the irreversible inhibition of GST P1-1[1][2].
Product Specifications
CAS Number
62959-30-2
UNSPSC
12352005
Target
Glutathione S-transferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bitc-sg.html
Smiles
S=C(NCC1=CC=CC=C1)SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@H](N)C(O)=O)=O
Molecular Formula
C18H24N4O6S2
Molecular Weight
456.54
References & Citations
[1]Meyer DJ, et al., Forward and reverse catalysis and product sequestration by human glutathione S-transferases in the reaction of GSH with dietary aralkyl isothiocyanates. Biochem J. 1995 Mar 1;306 (Pt 2) (Pt 2) :565-9.|[2]Mathan Kumar S, et al., Regulation of Glutathione in Health and Disease with Special Emphasis on Chronic Alcoholism and Hyperglycaemia Mediated Liver Injury: A Brief Perspective[J]. Springer Science Reviews, 2014, 2: 1-13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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