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NSC5844

NSC5844 (RE-640) is a 4-aminoquinoline derivative, with antitumor and antimalarial activity.

Product Specifications

CAS Number

[140926-75-6]

Product Name Alternative

RE-640

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/NSC5844.html

Purity

98.0

Solubility

DMSO : 1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

ClC1=CC=C2C(NCCNC3=CC=NC4=CC(Cl)=CC=C34)=CC=NC2=C1

Molecular Formula

C20H16Cl2N4

Molecular Weight

383.27

Precautions

H302, H315, H319

References & Citations

[1]Zhang H, et al. Synthesis and in vitro cytotoxicity evaluation of 4-aminoquinoline derivatives. Biomed Pharmacother. 2008 Feb;62 (2) :65-9. Epub 2007 May 24.|[2]Vennerstrom JL, et al. Bisquinolines. 1. N, N-bis (7-chloroquinolin-4-yl) alkanediamines with potential against chloroquine-resistant malaria. J Med Chem. 1992 May 29;35 (11) :2129-34.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Plasmodium

Available Sizes

Curated Selection

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