NSC5844
NSC5844 (RE-640) is a 4-aminoquinoline derivative, with antitumor and antimalarial activity.
Product Specifications
CAS Number
[140926-75-6]
Product Name Alternative
RE-640
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/NSC5844.html
Purity
98.0
Solubility
DMSO : 1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
ClC1=CC=C2C(NCCNC3=CC=NC4=CC(Cl)=CC=C34)=CC=NC2=C1
Molecular Formula
C20H16Cl2N4
Molecular Weight
383.27
Precautions
H302, H315, H319
References & Citations
[1]Zhang H, et al. Synthesis and in vitro cytotoxicity evaluation of 4-aminoquinoline derivatives. Biomed Pharmacother. 2008 Feb;62 (2) :65-9. Epub 2007 May 24.|[2]Vennerstrom JL, et al. Bisquinolines. 1. N, N-bis (7-chloroquinolin-4-yl) alkanediamines with potential against chloroquine-resistant malaria. J Med Chem. 1992 May 29;35 (11) :2129-34.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
Available Sizes
Curated Selection
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